Title : Apolipoprotein E 4 accelerates dementia and increases cerebrospinal fluid tau levels in Alzheimer ' s disease
نویسندگان
چکیده
Correspondence and reprint requests to: Dr. Mitsuyasu Kanai Department of Neurology, Gunma University School of Medicine, Phone Number: +81-27-220-8061, Facsimile Number: +81-27-220-8068, E-mail: [email protected] This manuscript consists of 1811 words in text, 120 words in abstract, 1 figure, 1 table and 20 references. Brief running head title: ApoE4 declines dementia and increases CSF tau level
منابع مشابه
Apolipoprotein E4 accelerates dementia and increases cerebrospinal fluid tau levels in Alzheimer's disease.
To examine the effect of apolipoprotein E (ApoE) 4 on the progression of Alzheimer's disease (AD), the clinical course of 33 AD patients (17 cases with ApoE epsilon4 and 16 cases without ApoE epsilon4) was evaluated with the mini-mental state examination (MMSE) and cerebrospinal fluid (CSF) biological markers. The decline of MMSE scores to zero was shortened in the ApoE4 group. During a mean fo...
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